Monday Night Football odds, line: 49ers vs. Cardinals prediction, Mexico City NFL picks by expert who's 13-3

In 2005, the Arizona Cardinals beat the San Francisco 49ers in the very first regular-season NFL video game ever played outside the United States. On Monday, the exact same 2 groups will fulfill in the exact same place for the 4th NFL in Mexico City video game. Estadio Azteca will display Monday Night Football, the last contest of Week 11. The 49ers are 5-4 this season, while the Cardinals are 4-6 after a 2-4 stretch over the last 6 video games.

Kickoff is at 8:15 p.m. ET in Mexico. Caesars Sportsbook notes the 49ers as 10-point favorites, while the over/under, or overall variety of points Vegas believes will be scored, is 42.5 in the most recent 49ers vs. Cardinals chances. Before you make any Cardinals vs. 49ers choices and NFL forecasts, you require to see what SportsLine’s leading 49ers professional, Micah Roberts, needs to state.

Roberts has actually operated in the Las Vegas sportsbook market for 20-plus years, consisting of a 13-year run as Station Casinos’ book director. Armed with a sophisticated network of sources, Roberts has unequaled details in several sports. He’s likewise on a 13-3 roll on his last 16 choices including the 49ers, making him the most well-qualified professional to choose Monday Night Football.

Now, Roberts has actually set his sights on 49ers vs. Cardinals and simply secured his choices and MNF forecasts. You can head to SportsLine now to see his choices. Now, here are numerous NFL chances and wagering lines for 49ers vs. Cardinals:

  • 49ers vs. Cardinals spread: 49ers -10
  • 49ers vs. Cardinals over/under: 42.5 points 
  • 49ers vs. Cardinals cash line: 49ers -480, Cardinals +360
  • SF: 49ers are 4-5 versus the spread this season 
  • AZ: Cardinals are 5-5 versus the spread this season 
  • 49ers vs. Cardinals chooses: See chooses here

Featured Game | Arizona Cardinals vs. San Francisco 49ers

Why the 49ers can cover

San Francisco has among the very best defenses in the league, headlined by a game-changer in Nick Bosa. He is a Pro Bowl protective end who led the NFL in takes on for loss in 2021. Bosa has 34 sacks in 43 profession video games and leads the league with 24 quarterback strikes this season. Bosa is likewise in the leading 3 of the NFL with 9.5 sacks, 45 pressures, and 11 takes on for loss.

As a group, San Francisco ranks in the leading 5 with 29 sacks and is No. 1 in overall backyards enabled (280.6 per video game), very first downs enabled, hurrying backyards enabled (82.7 per video game), and backyards enabled per rush effort (3.4). The 49ers are likewise in the leading 5 in points enabled per video game (18.1), points enabled per drive (1.60), and backyards enabled per drive (27.2). San Francisco is strong versus the pass, holding challengers to 197.9 backyards per through the air, and the 49ers have actually enabled just 9 passing goals and 5.6 net backyards per pass effort. See which group covers here.

Why the Cardinals can cover

Arizona can surges on offense. The Cardinals are above the NFL average in producing 23.0 points per video game and have 206 very first downs this season. Arizona looks after the ball with only 9 turnovers in 10 video games and works near the objective line, publishing a 60.0% red zone effectiveness.

San Francisco is below-average in turnover production on defense with just 10 takeaways and quits a goal on 61.9% of red zone journeys. On the opposite, Arizona likewise develops havoc with 14 turnovers, a top-10 mark in the NFL, and the Cardinals are fit to slow San Francisco’s run-heavy offense with 4.4 backyards enabled per bring and 110.5 hurrying backyards enabled per video game. San Francisco likewise has 13 turnovers in 9 video games on offense, consisting of 7 lost fumbles. See which group covers here.

How to make 49ers vs. Cardinals choices

Roberts has actually examined this match and while we can inform you he’s leaning Over on the point overall, he has actually likewise found a vital X-factor that has him leaping all over one side of the spread. He’s just sharing what it is, and which side to back, at SportsLine.

Who wins Cardinals vs. 49ers on Monday Night Football in Mexico City? And which crucial X-factor makes one side of the spread a must-back? Visit SportsLine now to see which side of the Cardinals vs. 49ers infected back, all from the professional who’s 13-3 on Niners choices, and discover.



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